Vito Cantisani MD, Presenter: Nothing to Disclose

Federico Marchetti, Abstract Co-Author: Nothing to Disclose

Valentina Lombardi, Abstract Co-Author: Nothing to Disclose

Ugo D'Ambrosio, Abstract Co-Author: Nothing to Disclose

Francesco Maria Drudi MD, Abstract Co-Author: Nothing to Disclose

Roberto Passariello MD, Abstract Co-Author: Nothing to Disclose

Paolo Ricci MD, Abstract Co-Author: Nothing to Disclose

Flores Calascibetta, Abstract Co-Author: Nothing to Disclose

et al, Abstract Co-Author: Nothing to Disclose

To compare CEUS and contrast-enhanced-MRI in the differentiation of a series of histologically proven bladder lesions detected at conventional cystoscopy.

Sixtifour consecutive patients (48 Male, 16 Females; mean age: 62 years) with known histologically bladder lesions (mean diameter of 2.5 cm; range: 1-4.5 cm), detected at conventional cystoscopy were prospectively evaluated with Sonovue enhanced-Low-mechanical index- US (CEUS) and MRI. Two experts evaluated in consensus the videos and scored the time arrival of contrast agent and enhancement behaviour. Subsequently time-intensity curves of all the lesions were assessed. A specific sonographic quantification software, was used to obtain contrast-enhanced sonographic perfusion maps and compared with corresponding curvers as provided by MRI. Mc Nemar test was then calculated.

All bladder lesions (36) seen on conventional cystoscopy were demonstrated with CEUS and mRI, which in addition detected two additional small lesions of 1 cm. Twenty malignant lesions and 16 benign tumours were histologically diagnosed. Sensitivity and specificity of CEUS and MRI were: 90%, 95%, and respectively. CEUS and MRI achieved high results with no statistical difference if compared with cystoscopy

CEUS and MRI are non-invasive reliable method to differentiate urinary bladder lesions, since it provides typical enhancement patterns, and contrast-sonographic specific perfusions curves.

CEUS is a non-invasive reliable method to differentiate urinary bladder lesions, since it provides typical enhancement patterns, and specific perfusions curves.

Cantisani, V, Marchetti, F, Lombardi, V, D'Ambrosio, U, Drudi, F, Passariello, R, Ricci, P, Calascibetta, F, et al, , Low Mechanical Index CEUS and Contrast-enhanced MRI in the Differentiation of Urinary Bladder Lesions.  Radiological Society of North America 2008 Scientific Assembly and Annual Meeting, February 18 - February 20, 2008 ,Chicago IL. http://archive.rsna.org/2008/6018541.html