Sina Speck MD, Presenter: Nothing to Disclose

Astrid Baur MD, Abstract Co-Author: Nothing to Disclose

Markus Hahn MD, Abstract Co-Author: Nothing to Disclose

Claus Detlef Claussen MD, Abstract Co-Author: Nothing to Disclose

Katja C. Siegmann MD, Abstract Co-Author: Nothing to Disclose

Analysis of movement of US- or MRI-guided placed localization coils in malignant breast tumors by mammographic evaluation to determine coil stability.

We analyzed digital mammograms of all patients (N=120), who received US- or MRI-guided breast cancer lesion localization using a coil (MREYE, Cook, Bjaeverskov, Denmark) from 01/2002 until 12/2007. 86 patients, who had at least one follow-up mammography in mediolateral (ml) and craniocaudal (cc) projection 3 days to 9 months after localization procedure, were included into the study. The coil location was documented on cc and ml view by means of a self-made template to obtain the 3D position of the coil. Deviation of the coil location from first to second mammography was calculated in millimetres (mm) based on the initially defined 3D position. Subsequently the movement of the coils was correlated with the interval since coil positioning, and with mammographic breast density according to BIRADS® (ACR 1-4).

To consider possible tissue shift due to preoperative wire localization of the coil 2 groups were analyzed separately: group A= all patients (N=86), group B= patients with at least two examinations without consideration of the mammogram after wire localization (N=50). Deviation of the coil location in group A (N=86): 27% <5mm, 38% 5-10mm, 26% 10-15mm, 6% 15-20mm, and 3% >20mm; in group B (N=50): 21% <5mm, 23% 5-10mm, 9% 10-15mm, 5% 15-20mm, and none >20mm. Coil movement was not significantly dependent from the interval since localization procedure (both groups p>0,05). Also no dependency of mammographic breast density (ACR 1-4) was recognizable (both groups p>0,05).  

Pretherapeutic US- or MRI-guided coil localization of malignant breast lesions allows sufficient tumor localization with a coil movement of 15 mm or less in 91% (group A) respectively 92% (group B) over a period of up to 9 months, e.g. in case of neoadjuvant therapy. The calculated coil movement is neither dependent from the interval since localization procedure nor from mammographic breast density.

US- or MRI-guided coil localization is a sufficient method for pretherapeutic tumor localization of malignant breast lesions.

Speck, S, Baur, A, Hahn, M, Claussen, C, Siegmann, K, Pretherapeutic Tumor Localization of Breast Cancer Using a Coil: Mammographic Longitudinal Study of Coil Movement.  Radiological Society of North America 2008 Scientific Assembly and Annual Meeting, February 18 - February 20, 2008 ,Chicago IL. http://archive.rsna.org/2008/6017299.html