Jin Hee Moon MD, Presenter: Nothing to Disclose

Hak Hee Kim MD, Abstract Co-Author: Nothing to Disclose

Hee Jung Shin MD, Abstract Co-Author: Nothing to Disclose

Myung-su Ko MD, Abstract Co-Author: Nothing to Disclose

Ju Young Lee MD, Abstract Co-Author: Nothing to Disclose

Hyun Ji Kim, Abstract Co-Author: Nothing to Disclose

To prospectively evaluate of the diagnostic accuracy of optical diffusion breast imaging in patient who underwent conventional ultrasound and then underwent surgery or biopsy.

We performed optical diffusion breast imaging after conventional ultrasound in 61 lesions. All patients underwent ultrasound-guided core needle biopsy or surgery. Two radiologists reviewed morphology and BIRADS category on conventional ultrasound and also reviewed diffusion features on supplemental optical diffusion imaging. Surgery and biopsy results served as reference standard. We compared the diagnostic accuracy including sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) between the results of conventional ultrasound and the supplemental use of diffusion optical imaging to conventional ultrasound.

Of the 61 lesions, forty-four lesions were malignancy and 17 lesions were benign. Conventional ultrasound gave a sensitivity of 97.9%, specificity of 21.4%, PPV of 80.7%, and NPV of 75.0%, whereas the supplemental use of optical diffusion imaging to conventional ultrasound gave a sensitivity of 95.8 %, specificity of 46.2 %, PPV of 86.8 %, and NPV of 75.0 %, respectively. The supplemental use of optical diffusion imaging decrease the benign biopsy results in 36.3 % (4/11).

The optical diffusion breast imaging might be an adjunctive tool to increase the diagnostic accuracy of the conventional ultrasound in differentiating malignant from benign breast lesions.

Supplemental use of optical diffusion imaging to the conventional ultrasound might help to differentiate benign from malignant lesions of the breast and also might reduce the negative biopsy results.

Moon, J, Kim, H, Shin, H, Ko, M, Lee, J, Kim, H, Supplemental Use of Optical Diffusion Breast Imaging for Differentiation between Benign and Malignant Breast Lesions.  Radiological Society of North America 2008 Scientific Assembly and Annual Meeting, February 18 - February 20, 2008 ,Chicago IL. http://archive.rsna.org/2008/6016353.html