Baskaran Sundaram MBBS, Presenter: Research grant, Bayer AG

Troy LaBounty, Abstract Co-Author: Nothing to Disclose

Elina Yamada, Abstract Co-Author: Nothing to Disclose

Prachi Agarwal MD, Abstract Co-Author: Nothing to Disclose

William Armstrong MD, Abstract Co-Author: Nothing to Disclose

Ella A. Kazerooni MD, Abstract Co-Author: Consultant, General Electric Company Consultant, Vital Images, Inc Research funded, General Electric Company

To compare AV characteristics between CT and Transesophageal Echocardiography (TEE)

This is a HIPPA compliant IRB approved retrospective comparison of AV characteristics between dynamic CT and TEE in 77 patients with AS. Grades of AV leaflet calcification (0-4), mobility (0-2), thickness (0-4) and number of leaflets (2 or 3) were blindly and independently (2 CT and 1 TEE readers) evaluated.

For AV calcification, CT readers substantially agreed (within 1 grade in 75/77 pts, k=0.72), and each had fair agreement with TEE (within 1 grade in 59/77 and 58/77 pts, k= 0.34 and 0.39). For AV mobility, CT readers had moderate agreement (64/77 pts, k=0.58) and individually with TEE (61/77 and 57/77 pts, k=0.53 and 0.48). For AV leaflet thickness, CT readers moderately agreed (within 1 grade in 70/77 pts, k=0.44), and each had fair agreement each with TEE (within 1 grade in 66/77 and 60/77 pts, k=0.24 and 0.26). CT had mean sensitivity of 86% and specificity of 81% to diagnose bicuspid valve with substantial agreement between CT readers (68/74 pts, k=0.84) and between CT readers and TEE (56/68 and 59/69 pts, k=0.65 and 0.71).

AV assessment using dynamic CT is feasible and it determines leaflet morphology precisely. CT grading of AV calcifications, mobility, and thickening has fair to moderate agreement with TEE.

Aortic valve (AV) morphology has prognostic implications. Preop knowledge of AV features in Aortic Stenosis (AS) helps to decide repair vs replacement(AVR), correct AVR procedure and the AV prosthesis

Sundaram, B, LaBounty, T, Yamada, E, Agarwal, P, Armstrong, W, Kazerooni, E, CT Characterization of Stenotic Aortic Valve.  Radiological Society of North America 2008 Scientific Assembly and Annual Meeting, February 18 - February 20, 2008 ,Chicago IL. http://archive.rsna.org/2008/6012947.html