Pure Rheumatoid Mitral Stenosis: Assessment of Right Ventricular Systolic and Left Ventricular Diastolic Function and Quantification of Severity on 64-Slice MDCT

SSA02-02

Pure Rheumatoid Mitral Stenosis: Assessment of Right Ventricular Systolic and Left Ventricular Diastolic Function and Quantification of Severity on 64-Slice MDCT

Scientific Papers

Presented on November 30, 2008
Presented as part of SSA02: Cardiac (Valves and Atrial Appendages: CT vs MR/Echocardiography)

Xiao-chun Zhang, Presenter: Nothing to Disclose

Zhi-gang Yang MD, PhD, Abstract Co-Author: Nothing to Disclose

To evaluate whether 64-slice MDCT can assess right ventricular systolic and left ventricular diastolic function and quantify severity of pure rheumatoid mitral stenosis (PRMS) in comparison to the transthoracic echocardiography (TTE).

Forty-three patients with PRMS (26 men, 17 women, mean age, 46±8 years) were enrolled in this study. All patients underwent retrospectively ECG-gated 64-slice MDCT and TTE for assessing right ventricular systolic and left ventricular diastolic function. Right ventricular end-systolic volume (RV-ESV), stroke volume (RV-SV), ejection fraction (RV-EF), cardiac output (RV-CO) and wall mass (RV-Mass), as well as left ventricular end-diastolic volume (LV-EDV), maximal mitral valve area(MVA) and maximal mitral valve annular area(MVAA) were measured with dedicated cardiac analysis software on 64-slice MDCT. Severity of mitral stenosis was classified by MVA with TEE and 64-MDCT.

RV-SV, RV-EF, RV-CO, RV-Mass, LV-EDV, MVA, and MVAA were significantly lower in patients with severe PRMS (n=15) than in patients with moderate (n=21) and mild PRMS (n=7, p<0.001). RVESV were significant higher in severe PRMS than in patients with moderate and mild PRMS (p<0.001). RV-ESV, RV-SV, RV-EF, RV-CO, RV-Mass and LV-EDV correlated well with MVA (r=-0.96, 0.97, 0.94, 0.87, 0.93, and 0.95, respectively; p<0.001).

The retrospectively ECG-gated 64-slice MDCT may provide an accurate, noninvasive imaging technique for assessing of ventricular function and quantifying severity of PRMS.

64-slice MDCT can quantitatively assess the ventricular function and severity in patients with PRMS and to provide useful information for clinical decision.

Zhang, X, Yang, Z, Pure Rheumatoid Mitral Stenosis: Assessment of Right Ventricular Systolic and Left Ventricular Diastolic Function and Quantification of Severity on 64-Slice MDCT. Radiological Society of North America 2008 Scientific Assembly and Annual Meeting, February 18 - February 20, 2008 ,Chicago IL. http://archive.rsna.org/2008/6007215.html