Xiao-chun Zhang, Presenter: Nothing to Disclose

Zhi-gang Yang MD, PhD, Abstract Co-Author: Nothing to Disclose

To determine whether the 64-slice MDCT can assess the right ventricular function in pure mitral stenosis with high accuracy and reproducibility when compared the results with those of MR imaging.

Right ventricular end-diastolic and end-systolic volume (RV-EDV and RV-ESV), stroke volume (RV-SV), ejection fraction (RV-EF), cardiac output (RV-CO), and wall mass (RV-Mass) were measured with dedicated cardiac analysis software on 64-slice MDCT and compared with values measured with MR imaging in 43 consecutively patients with pure rheumatoid mitral stenosis (23 men, 20 women; mean age, 45±9 years). Diagnostic test was performed in all patients with retrospectively ECG-gated 64-MDCT.

No significant differences were revealed in calculated right ventricular function parameters between the two methods. RV-EDV, RV-ESV, RV-SV, RV-EF, RVCO, and RV-Mass by 64-slice MDCT (136.5 ± 21.3 ml, 80.1 ±15.0 ml, 56.4 ±19.9 ml, 40.6 ±11.3 %, 3578.4 ±785.4 ml and 93.3 ± 11.6g ) were similar to those by MRI (136.7±21.0 ml, 81.1 ± 15.4 ml, 55.6 ± 19.2 ml, 40.1 ± 11.5%, 3552.3 ± 836.3 ml and 95.9 ±13.0g). There were good correlations (r=0.98, 0.97, 0.96, 0.96, 0.95 and 0.77, respectively) and close agreement. The variability in 64-slice MDCT measurements was similar to that in MR imaging values (bias=-0.2ml, -1.0ml, 0.8ml, 0.5%, 26.1ml, and 0.5g; p>0.05). In measurement of right ventricular function by 64-sliceMDCT, the highest sensitivity, specificity, accuracy, negative predictive value, and positive predictive value were obtained with RV-ESV, RV-SV, RV-EF, RVCO and RV-Mass.

The retrospectively ECG-gated 64-slice MDCT could assess the right ventricular function in mitral stenosis with high accuracy and reproducibility when compared to MR imaging.

64-slice MDCT can noninvasive assess right ventricular function, and may have applications in dysfunction of right ventricle in patients with pure rheumatoid mitral stenosis.

Zhang, X, Yang, Z, Accuracy and Reproducibility of Assessing Right Ventricular Function for Patients with Pure Rheumatoid Mitral Stenosis on 64-Slice MDCT: Comparison with MR Imaging.  Radiological Society of North America 2008 Scientific Assembly and Annual Meeting, February 18 - February 20, 2008 ,Chicago IL. http://archive.rsna.org/2008/6007213.html