Yonggang Li MD, Presenter: Nothing to Disclose

Liang Guo, Abstract Co-Author: Nothing to Disclose

To explore the application value of diffusion weighted imaging(DWI) and diffusion tensor imaging(DTI) in the differetiation diagnosis between benign and malignant soft tissue tumors.

Of 34 cases of soft tissue tumors, there are 14 cases of benign tumors and 20 cases of malignant tumors. MRI and DWI/DTI were performed on all cases, then the images were transmitted to AW4.0 workstation. The apparent diffusion coefficient (ApDC), average diffusion coefficient(AvDC), fractional anisotropy(FA), isotropic(Iso), volume ratio anisotropy(VrA) of the central parenchyma area, the necrosis area, the peripheral area of the tumor and the normal muscle around the tumor were calculated and analyzed. The correlation study between MRI and pathology was done.

The ADC and average ADC of the central parenchyma area and the peripheral area between the benign and malignant soft tissue tumors had significant statistical difference（P<0.01）. The difference of FA , ISO and VrA of the peripheral area between the benign and malignant soft tissue tumors was statistically significant（P<0.01）, but there was no difference in the central parenchyma area of 34 cases of tumors. On pathological inspection, 14 of 16 cases of malignant soft tissue tumors demonstrated undiscriminated borders with the normal muscle. Of 14 cases of benign soft tissue, 11 cases revealed the entire capsule around the tumors and the clear borders with the normal muscle.

DWI and DTI are beneficial to demonstrate the structure of soft tissue tumors and its border and have great application value in the differentiating diagnosis of benign and malignant soft tissue tumor.

DWI/DTI have great application value in the differentiating diagnosis of benign and malignant soft tissue tumor

Li, Y, Guo, L, Correlation Study between Diffusion-weighted Imaging and Pathology of Benign and Malignant Soft-tissue Tumor in Human.  Radiological Society of North America 2007 Scientific Assembly and Annual Meeting, November 25 - November 30, 2007 ,Chicago IL. http://archive.rsna.org/2007/5016182.html