Srikanth Reddy Boddu MBBS, MRCS, Presenter: Nothing to Disclose

Timothy Jaspan MD, Abstract Co-Author: Nothing to Disclose

Robert Lenthall, Abstract Co-Author: Nothing to Disclose

Norman McConachie, Abstract Co-Author: Nothing to Disclose

Allan Christopher Thomas MBBS, Abstract Co-Author: Nothing to Disclose

The study aims to identify which angioarchitectural features of brain AVMs were significantly associated with initial clinical presentation of haemorrhage in our population.

The initial clinical presentation, angioarchitectural features of all the brain AVM patients admitted to our tertiary referral centre for neuroradiology and neurosurgery during 1995 - 2006 were reviewed retrospectively. The clinical details and angioarchitectural features were obtained from clinical case notes. Films were reviewed by consultant neuroradiologist. The statistical association of the angiographic features were studied using chi-square test. Significance of this association was confirmed using odds ratio and phi value.

We reviewed a total of 180 patients during this period. 92 patients presented with haemorrhage as initial clinical manifestation. The analysis from our study reveals that smaller AVMs ( 6cm) [small AVM p <0.01; phi-0.21]. The size of AVM is inversely related to initial haemorrhagic presentation [medium AVM p<0.02; phi – 0.17; large AVM p <0.05; phi – 0.15]. In addition deep venous drainage [p <0.01; phi – 0.21], single draining vein [p <0.001; phi – 0.25] and location in thalamus [p <0.01; phi – 0.25] revealed significant association with initial haemorrhagic presentation.

In the angioarchitectural features, smaller AVM size, deep venous drainage, single draining vein and location in thalamus are significantly associated with initial haemorrhagic presentation.

In the angiographic features of brain AVMs, smaller AVM size, deep venous drainage, single draining vein and location in thalamus are significantly associated with initial haemorrhagic presentation.

Boddu, S, Jaspan, T, Lenthall, R, McConachie, N, Thomas, A, The Angioarchitectural Features Associated with Haemorrhage, at Presentation, in the Nottingham Brain AVM Cohort.  Radiological Society of North America 2007 Scientific Assembly and Annual Meeting, November 25 - November 30, 2007 ,Chicago IL. http://archive.rsna.org/2007/5015414.html