Vito Cantisani MD, Presenter: Nothing to Disclose

Paolo Ricci MD, Abstract Co-Author: Nothing to Disclose

Carlo Catalano MD, Abstract Co-Author: Nothing to Disclose

Ugo D'Ambrosio, Abstract Co-Author: Nothing to Disclose

Daniele Marin MD, Abstract Co-Author: Nothing to Disclose

Roberto Passariello MD, Abstract Co-Author: Nothing to Disclose

Guido Alfano, Abstract Co-Author: Nothing to Disclose

Luisa Coletta MD, Abstract Co-Author: Nothing to Disclose

Enrico Cortesi, Abstract Co-Author: Nothing to Disclose

et al, Abstract Co-Author: Nothing to Disclose

et al, Abstract Co-Author: Nothing to Disclose

To evaluate US and low-MI CEUS for the detection of hepatic metastases from colorectal tumours by using 64 slice spiral CT/BOPTA-MRI as reference imaging modality

From February 2005 to October 2006 130 consecutive patients with colorectal tumours (72 males, 58 females; mean age 63 years; range 36-79) with known hepatic lesions underwent US and CEUS, and compared with contrast-enhanced 64-slice spiral CT and/or BOPTA-MRI. A follow-up for more than 6 months by using CT, MRI or intraoperative biopsy (55 patients) was considered the gold standard. McNemar test was calculated to compare US, and CEUS sensitivity and specificity

CEUS improved US sensitivity and specificity for the detection of individual metastases from 58% to 93% (P <.001) and from 52% to 92%, respectively, for lesions <1 cm (p<0.001). Sensitivity of US, CEUS, CT and MRI in the patients who underwent intraoperative US were 48%, 89%, 89%, and 91%, respectively.

CEUS is significantly more accurate than US and roughly comparable with CT and MRI in the detection of liver metastases from colorectal cancer. Therefore, in the evaluation of patients with suspected hepatic metastases from colorectal tumour, US examination must be performed after contrast administration

In the evaluation of patients with suspected hepatic metastases from colorectal tumour, US examination must be performed after contrast administration

Cantisani, V, Ricci, P, Catalano, C, D'Ambrosio, U, Marin, D, Passariello, R, Alfano, G, Coletta, L, Cortesi, E, et al, , et al, , Optimal Detection of Hepatic Metastases from Colorectal Tumours: Prospective Evaluation of US and Low Mechanical Index (MI) Real-time Contrast-enhanced US as Compared with 64 Slice-CT or BOPTA-MRI.  Radiological Society of North America 2007 Scientific Assembly and Annual Meeting, November 25 - November 30, 2007 ,Chicago IL. http://archive.rsna.org/2007/5013160.html