M.Teresa Maristany MD, Presenter: Nothing to Disclose

Marisa Ortega-Sanchez, Abstract Co-Author: Nothing to Disclose

Sergi Vidal-Sicart MD, Abstract Co-Author: Nothing to Disclose

Jose Royo MD, Abstract Co-Author: Nothing to Disclose

Ivan Vollmer MD, Abstract Co-Author: Nothing to Disclose

Mar Vernet MD, Abstract Co-Author: Nothing to Disclose

Francesc Ferrer MD, Abstract Co-Author: Nothing to Disclose

et al, Abstract Co-Author: Nothing to Disclose

et al, Abstract Co-Author: Nothing to Disclose

To detect the SLN and localize the non-palpable breast lesions by means the same radiotracer injection into the tumor.

One hundred and ten consecutive female patients with breast cancer lesions were scheduled to perform a tumoral excision and SLN localization. Group A: 53 patients with palpable lesion. Group B: 40 patients with non palpable lesions were localized with ROLL. Group C: 17 patients with microcalcifications. The day before the surgery a lymphoscintigraphy was performed by injecting 111 MBq of 99mTc-nanocolloid, in 0.5 ml volume, intratumorally/intradermally (group A and group C, respectively). The group B patients received the same dose intratumorally and guided by ultrasonography but in a 0.2 ml volume in order to better concentrate the dose into the tumour. Static images were done at 30 min and 2-4 hours after injection. When the SLN was identified, it was externally marked on the skin with indelible ink. During surgery the SLN was localized by using a hand-held gamma probe, and, specifically in group B patients the tumoral harvesting was guided by the probe.

Group A: Lymphoscintigraphy identified the SLN in 51 patients (96%). In 5 patients the SLN was located in the internal mammary chain (9,4%). Group B: Succesful tumoural excision was performed with the gamma probe in 38 patients (95%). In the remaining 2 patients an enlargement of surgery was performed due to an unclear margins excision. The SLN was identified in 39 patients (97%) in the axillary region, and in 6 women in the internal mammary chain (15%). Group C: Lymphoscintigraphy identified the SLN in the axillary region in all cases (100%).

In our study, there were similar rates of excision in A (palpable) and B (non-palpable lesions) groups. This technique allowed also to detect internal mammary chain adenopathies.

ROLL is a quick and simple technique that achieves a high rate of clear margins of the tumour and is possible to be performed with the sentinel lymph node identification by only injecting one radiotracer dose.

Maristany, M, Ortega-Sanchez, M, Vidal-Sicart, S, Royo, J, Vollmer, I, Vernet, M, Ferrer, F, et al, , et al, , Breast Cancer: Radioguided Occult Lesion Localization (ROLL) and Sentinel Lymph Node Detection with Only One Radiotracer Injection.  Radiological Society of North America 2007 Scientific Assembly and Annual Meeting, November 25 - November 30, 2007 ,Chicago IL. http://archive.rsna.org/2007/5010923.html