Seon Hyeong Choi, Presenter: Nothing to Disclose

Eun-Kyung Kim, Abstract Co-Author: Nothing to Disclose

Jin Young Kwak MD, Abstract Co-Author: Nothing to Disclose

Min Jung Kim MD, Abstract Co-Author: Nothing to Disclose

Ki Keun Oh MD, Abstract Co-Author: Nothing to Disclose

To evaluate the diagnostic accuracy and clinical role of the US- guided 14-gauge automated core needle biopsy for phyllodes tumors of the breast in large series

The institutional review board approved this retrospective study; the informed consent requirement has been waived. Among 99 patients with surgically proven phyllodes tumors from September 2002 to August 2006, 56 patients who have undergone preoperative 14-gauge core needle biopsy were included in this study. There were benign (n=40), borderline (n=8) and malignant phyllodes (n=8) tumors. Histologic concordance between core biopsy and surgical specimen, and the accuracy of diagnosing benign and malignant phyllodes tumor were analyzed.

The diagnosis of preoperative core biopsy was as follows: phyllodes tumors (n=21), biphasic tumor (n=8), fibroadenoma (n=11), fibroadenomatous hyperplasia (n=7), and other benign masses (n=9). The diagnostic accuracy was 51.7% (29/56) including biphasic tumor. In the suggesting phyllodes tumors on core biopsy (n=29), the correct diagnosis of malignant tumor was not made on 14-gauge core biopsy except 1 case.

The US-guided 14-gauge core biopsy was not accurate for diagnosing phyllodes tumor of breast and furthermore, the distinction between benign and malignant phyllodes tumor was not possible.

14-gauge core biopsy can help to diagnose phyllodes tumors of breast but not sufficient, so surgical excision is needed.

Choi, S, Kim, E, Kwak, J, Kim, M, Oh, K, Diagnostic Accuracy and Clinical Role of the US-guided 14-gauge Automated Core Biopsy for Phyllodes Tumors of the Breast.  Radiological Society of North America 2007 Scientific Assembly and Annual Meeting, November 25 - November 30, 2007 ,Chicago IL. http://archive.rsna.org/2007/5005887.html