Hao Shi MD, Abstract Co-Author: Nothing to Disclose

Hong Yu Ding MD, Abstract Co-Author: Nothing to Disclose

Rui Ping Duan MD, Abstract Co-Author: Nothing to Disclose

Xiangtao lin MD, Presenter: Nothing to Disclose

To study the method and the findings of MR perfusion weighted imaging (PWI) in normal kidney and renal diseases.

Thirty-three cases, who include 9 volunteers, 14 cases with renal carcinoma, 6 cases with renal cyst, 2 cases with renal angiomyolipoma and 2 cases with renal tuberculosis, were examined with T1WI, T2WI and PWI. MR examinations were performed with and dynamic EPI-T2* perfusion. The data from the cases were processed with workstation to obtain time-singal intensity curves, color perfusion maps and relative perfusion value. The relative renal blood volume (rRBV), the relative renal blood flow (rRBF), the mean Transition Time (MTT) and the time to peak (TTP) in the normal renal cortex and medulla and the renal lesions were calculated.

After the treatment of statistics, the results showed that rRBV and rRBF of the cortex was greater than that of the medulla in the normal kidneys (p<0.01 and p<0.01)；MTT and TTP of the cortex was shorter than that of the medulla in the normal kidneys (p<0.01 and p<0.05). The values of rRBF and TTP of the renal carcinoma were evidently high than the normal tissues (p<0.01). The values of rRBV and rRBF of the renal cysts distinctly decreased (p<0.01) and MTT and TTP lengthened (p<0.01). The value of rRBV of the renal angiomyolipoma and the renal tuberculosis was distinctly decreased (p<0.01).

PWI can demonstrate the hemodynamic and the functional state of the normal renal tissues and the renal lesions and will become an ideal method for showing the morphological and functional changes of the kidney.

The renal PWI has been used in the routine examination of renal lesions in our institute and was valuable in differentiating the renal diseases and judging the renal function.

Shi, H, Ding, H, Duan, R, lin, X, Study of Renal MR Perfusion-weighted Imaging.  Radiological Society of North America 2007 Scientific Assembly and Annual Meeting, November 25 - November 30, 2007 ,Chicago IL. http://archive.rsna.org/2007/5002623.html