Yining Wang MD, Presenter: Nothing to Disclose

Zheng Yu Jin, Abstract Co-Author: Nothing to Disclose

Zhuhua Zhang MD, Abstract Co-Author: Nothing to Disclose

Lan Song MD, Abstract Co-Author: Nothing to Disclose

Liren Zhang, Abstract Co-Author: Nothing to Disclose

Shuyang Zhang MD, Abstract Co-Author: Nothing to Disclose

To investigate the characteristics of coronary artery lesions of patients with unstable angina as compared to patients with stable angina.

60 patients, 30 with unstable angina (UA) and 30 with stable angina (SA), underwent both ECG-gated CT Angiography (CTA) (120kV, 850mAs, 0.33 s-rotation time, 64 x 0.6 mm collimation，Siemens Somatom Sensation 64) and conventional quantitative coronary angiography (QCA). For each patient the Agatston Score was determined and the number of non-calcified plaques was calculated. All coronary segments were assessed quantitatively using syngo Circulation software and compared to QCA. hs-CRP levels were determined with the ELISA essay.

Within UA group, QCA found 23 (77%) patients with 70 significantly diseased segments. 66 of these were detected on CTA: 56（85％）non-calcified dominant plaques and 10(15%) calcified dominant plaques. CTA also detected 45 % (5/11) mild stenoses with non-calcified dominant plaques , 55% (6/11) with calcified dominant plaques .Within SA group, QCA found 21(70%) patients with 62 significantly diseased segments. 59 of these were detected on CTA: 40（68％）non-calcified dominant plaques and 19(32%) calcified dominant plaques. CTA also detected 17% (1/6) mild stenoses with non-calcified dominant plaques , 83%(5/6) with calcified dominant plaques. Calcium scores of UA group and SA group were165.4±251.0 and 218.5±346.9 ,respectively, (Z=-0.037, P>0.05). hs-CRP levels of UA group were significantly higher than those of SA group (median values: 4.21 vs. 0.83, P<0.05).

Patients with UA tend to have more significant stenoses related to non-calcified dominant plaques and show higher hs-CRP levels than do patients with SA. CTA can detect early coronary lesions before severe stenoses come out.

64-slice CTA can detect early coronary lesions and identify coronary lesions as calcified and non-calcified. It is recommended in the initial evaluation of suspected CAD.

Wang, Y, Jin, Z, Zhang, Z, Song, L, Zhang, L, Zhang, S, MSCT Imaging of Coronary Artery Lesions in Patients with Unstable Angina: Comparison with Patients with Stable Angina.  Radiological Society of North America 2006 Scientific Assembly and Annual Meeting, November 26 - December 1, 2006 ,Chicago IL. http://archive.rsna.org/2006/4441021.html Accessed October 8, 2025