Phalla Ou MD, Presenter: Nothing to Disclose

Gabriella Agnoletti PHD, Abstract Co-Author: Nothing to Disclose

Pascal Vouhe, Abstract Co-Author: Nothing to Disclose

Damien Bonnet, Abstract Co-Author: Nothing to Disclose

Daniel Sidi, Abstract Co-Author: Nothing to Disclose

Francis Brunelle, Abstract Co-Author: Nothing to Disclose

To prospectively evaluate the accuracy of 64- slice computed tomography (CT) angiography in detecting complications of the retransferred coronary arteries in long-term follow-up of children having undergone the arterial switch operation for transposition of the great arteries.

The local research ethics committee approved this study, and the subjects and/or a parent or guardian gave informed written consent. Ninety-five children (age 5.5 +/- 0.8 years) operated by the arterial switch operation underwent systematic conventional and CT coronary angiography. Ability of CT angiography in detecting stenosis and other modifications of the coronary arteries was analyzed by 2 independent investigators.

When compared to conventional coronary angiography, CT was able to assess all ostia and proximal segments of coronary arteries. It correctly detected the 8 patients (8.4%) with significant coronary lesions that had been identified by means of conventional angiography. The sensibility and specificity of the 64-slice CT are of 100% for detecting complications at the ostial segments, proximal segments, or both of the retransferred coronary arteries.

The results of our study suggest that 64-slice CT angiography is a viable non-invasive modality that could be an alternate to conventional angiography for the follow-up of children having undergone the arterial switch operation for transposition of the great arteries.

Our study suggests the following guidelines already applied in our institution: 64-slice CT can replace conventional angiography for the surveillance of children operated by arterial switch operation

Ou, P, Agnoletti, G, Vouhe, P, Bonnet, D, Sidi, D, Brunelle, F, Sixty-four-Slice CT Coronary Angiography in Children: Impact on Clinical Management after the Arterial Switch Operation for Transposition of the Great Arteries.  Radiological Society of North America 2006 Scientific Assembly and Annual Meeting, November 26 - December 1, 2006 ,Chicago IL. http://archive.rsna.org/2006/4440710.html