Rongjian Hu MD, Presenter: Nothing to Disclose

Zhiming Yao MD, Abstract Co-Author: Nothing to Disclose

Pan Jishu MD, Abstract Co-Author: Nothing to Disclose

To assess the value of PET/CT in the differential diagnosis of malignant and benign pancreatic lesions and compared PET/CT with contrast-enhanced CT (CECT).

The whole body 18F-FDG PET/CT and abdominal CECT were performed in 15 patients with malignant pancreatic lesions and 5 patients with benign pancreatic lesions .The pancreatic 18F-FDG PET/CT at 120 minutes delay were performed in 10 of those. patients. The maximum standardized uptake value (SUVmax) of pancreatic lesions was measured in 60 and 120 minutes. The diagnosis were made by PET, CECT and PET/CT respectively, and compared the final results of them. The final diagnostic results were made by pathology(n=11) or clinical and radiological diagnoses and morn than 6 months follow-up .

The SUVmax of benign and malignant pancreatic lesions were 2.42±1.54 and 6.74±3.54, respectively. There is significantly difference between the SUVmax of benign and malignant pancreatic lesions (t=-2.61, p<0.05). The 120-minutes-delay SUVmax of pancreatic lesions increased significantly more than 10% in the nine patients (n=1, benign and n=8, malignant). The PET and CECT diagnosed all benign pancreatic lesions accurately. Among 15 patients with malignant pancreatic lesions, there were 1 false negative case and 1 false positive case in PET diagnosis, while there were 2 false negative cases in CECT diagnosis. The all malignant or benign pancreatic lesions diagnosed by PET/CT were correctly. The diagnosis accuracy of CECT、 PET and PET-CT in malignant pancreatic lesions were 90％，90％ and 100%, respectively. Otherwise, the PET/CT can detected more metastases lesions in liver, lymph nodes and bone (31, 41 and 9, respectively) than CECT (16, 24 and 3, respectively).

The PET/CT is a useful tool in the differential diagnosis of malignant and benign pancreatic lesions. The combination of PET and CECT can profit to enhance the accuracy in diagnosis and staging of malignant pancreatic tumors.

It is useful for differential diagnosis and staging of pancreatic tumors.

Hu, R, Yao, Z, Jishu, P, The Value of PET/CT in Differential Diagnosis of Malignant and Benign Pancreatic Lesions.  Radiological Society of North America 2006 Scientific Assembly and Annual Meeting, November 26 - December 1, 2006 ,Chicago IL. http://archive.rsna.org/2006/4429880.html