Masaki Ishida MD, Presenter: Nothing to Disclose

Hajime Sakuma MD, Abstract Co-Author: Nothing to Disclose

Kakuya Kitagawa MD, Abstract Co-Author: Nothing to Disclose

Yasutaka Ichikawa MD, Abstract Co-Author: Nothing to Disclose

Nanaka Ishida MD, Abstract Co-Author: Nothing to Disclose

Noriyuki Kato MD, Abstract Co-Author: Nothing to Disclose

Kan Takeda MD, Abstract Co-Author: Nothing to Disclose

et al, Abstract Co-Author: Nothing to Disclose

1. To review concept and method of pharmacological stress test.  2. To explain how to optimize pulse sequence, study protocol and interpretation of stress perfusion MRI.  3. To illustrate imaging pitfalls and how to avoid them.  4. To demonstrate diagnostic value of stress myocardial perfusion MRI in patients with ischemic heart disease.

First-pass contrast enhanced MRI with pharmacological stress can provide detection of reduced myocardial perfusion reserve caused by flow limiting stenosis in the coronary artery.  Several recent studies including those from our group demonstrated excellent diagnostic accuracy of stress myocardial perfusion MRI in detecting significant coronary artery disease. However, this method requires an administration of adenosine or dipyridamole in the magnet, and there are several important points in acquisition and interpretation of MR images to achieve high sensitivity and specificity.  In this presentation, we demonstrate how radiologists can safely perform pharmacological stress in MR room, explain optimizations of pulse sequences and study protocol of stress perfusion MRI, and illustrate pitfalls in interpreting images by showing representative cases with movies.  We summarize diagnostic accuracy of this technique in patients with suspected IHD and those after coronary interventions

Ishida, M, Sakuma, H, Kitagawa, K, Ichikawa, Y, Ishida, N, Kato, N, Takeda, K, et al, , Stress Myocardial Perfusion MRI: Techniques, Pitfalls, and Diagnostic Value in Patients with Ischemic Heart Disease.  Radiological Society of North America 2005 Scientific Assembly and Annual Meeting, November 27 - December 2, 2005 ,Chicago IL. http://archive.rsna.org/2005/4421016.html