Wolfgang Matzek MD, Presenter: Nothing to Disclose

Wolfgang Schima MD, Abstract Co-Author: Nothing to Disclose

Katja Pinker MD, Abstract Co-Author: Nothing to Disclose

Johannes Zacherl MD, Abstract Co-Author: Nothing to Disclose

Roland Sedivy MD, Abstract Co-Author: Nothing to Disclose

Ahmed Ba-Ssalamah MD, Abstract Co-Author: Nothing to Disclose

To correlate high resolution hydro-multidetector-row CT (HMDCT) results with pathological findings in T staging of gastric carcinoma.

We examined 78 patients (median age=63) with gastric cancer diagnosed by endoscopic biopsy prior to surgery using HMDCT. Scans were performed either using a 4 or 16 channel scanner (4x1 and 16x0.75 respectively). Distention of the stomach was achieved with 1 to 1.5L of water immediately prior to the examination. Further, a spasmolytic agent was administered intravenously. The HMDCT was prospectively analyzed using accurately defined criteria: Tumor extension, tumor depth, wall enhancement and pattern, fat plane and infiltration of adjacent organs. Each case was staged according to the TNM classification and correlated with histopathological findings after surgery. For statistical analysis, a Wilcoxon-signed rank test was performed, as well as Spearman's test to compare correlation between HMDCT and histopathological findings.

From a total of 78 gastric cancers, 75 were detected in HMDCT. Three T1 cancers could not be detected. In 54 cases, the T-staging using HMDCT has well correlated with the histopathological results. 11 cases were understaged, 13 cases were overstaged. Sensitivity of HMDCT for detection of gastric cancer is 0.962 (95%-CI 0.892-0.992).

Hydro-multidetector-row CT as a noninvasive method presents as a very valuable tool in the preoperative staging of gastric cancer.

Matzek, W, Schima, W, Pinker, K, Zacherl, J, Sedivy, R, Ba-Ssalamah, A, Efficacy of Hydro-multidetector-row CT in T Staging of Gastric Cancer.  Radiological Society of North America 2005 Scientific Assembly and Annual Meeting, November 27 - December 2, 2005 ,Chicago IL. http://archive.rsna.org/2005/4418904.html