Abstract Archives of the RSNA, 2005
Neurogenic Arthrogryposis Multiplex Congenita Caused by Bilateral Polymicrogyria: Prenatal and Postnatal Imaging Findings
Presented on November 27, 2005
Selected for Possible Publication
Cristina Auger MD, Presenter: Nothing to Disclose
Elida Vazquez MD, Abstract Co-Author: Nothing to Disclose
Joaquim Piqueras MD, Abstract Co-Author: Nothing to Disclose
Manuel Roig MD, Abstract Co-Author: Nothing to Disclose
Elena Carreras MD, Abstract Co-Author: Nothing to Disclose
Goya Enriquez MD, Abstract Co-Author: Nothing to Disclose
To present the neurologic pre- and postnatal imaging findings in the 'Fetal Akinesia-Arthrogryposis Sequence' (FAAS), a multietiologic clinical syndrome caused by muscular inactivity in utero.
For didactic purposes, we present a brief review and correlation of clinical and imaging findings.
We present a retrospective review of children with diagnosis of FADS due to different pathological entities, seen in a tertiary pediatric center during the last fourteen years.
The spectrum of diagnosis found encompasses agyria-pachygyria, neuronal migration abnormalities, agenesis of the corpus callosum, hypoplasia of the brainstem and cerebellum, mitochondrial cytopathies, or hypoxic-ischemic lesions.
A total of 7 newborn patients were found to have neurogenic arthrogryposis multiplex congenita (AMC) with associated neuronal migration abnormalities.
Cortical brain malformation discovered on neonatal US and/or MRI were bilateral polymicrogyria, most often perisilvian polymicrogyria, with occasional associated heterotopias.
FADS is the result of a wide spectrum of diseases that in many instances can be identified by imaging.
Neurogenic Arthrogryposis Multiplex Congenita Caused by Bilateral Polymicrogyria: Prenatal and Postnatal Imaging Findings. Radiological Society of North America 2005 Scientific Assembly and Annual Meeting, November 27 - December 2, 2005 ,Chicago IL. http://archive.rsna.org/2005/4416576.html