Eito Kozawa, Presenter: Nothing to Disclose

Naoko Nishi MD, Abstract Co-Author: Nothing to Disclose

Atsuko Heshiki MD, Abstract Co-Author: Nothing to Disclose

Hidekazu kayano, Abstract Co-Author: Nothing to Disclose

To show diagnostic power of in-phase and opposed-phase imaging with respect to clinical stage of aplastic anemia.

Purpose: To compare between signal intensity ratio (SIR) of opposed-phase and in-phase imaging ratio in patient with aplastic anemia (AA) and bone marrow (BM) histology. Materials and methods: Twenty-seven patients of AA were classified by three clinical stages: mild type (n=12), moderate type (n=8), and severe type (n=7). The FLASH sequence with opposed-phase and in-phase images was obtained at 110/2.3 and 110/ 4.7. Opposed-phase and in-phase imaging were measured over a region of interest in the spinal vertebra, and SIR=opposed phase / in-phase was calculated. The results were confirmed by BM aspiration. SIRs were compared to BM histology and clinical stage. Results: The SIRs of patients with AA can vary greatly (range 0.23 -1.13, mean 0.68, SD 0.24). Mild type of AA yields low values of SIR and severe type of AA yields high values. Correlation between SIR and BM data of AA was shown. Conclusion: In-phase and opposed- phase imaging can be helpful predict the clinical stage of AA.

Kozawa, E, Nishi, N, Heshiki, A, kayano, H, MRI of Aplastic Anemia: Signal Intensity Ratio of In-Phase and Opposed-Phase Imaging—Pathogical and Clinical Correlation.  Radiological Society of North America 2005 Scientific Assembly and Annual Meeting, November 27 - December 2, 2005 ,Chicago IL. http://archive.rsna.org/2005/4410458.html