Winfried Albert Willinek MD, Presenter: Nothing to Disclose

Marcus M. Von Falkenhausen MD, Abstract Co-Author: Nothing to Disclose

Horst Urbach MD, Abstract Co-Author: Nothing to Disclose

Juergen Gieseke, Abstract Co-Author: Nothing to Disclose

Romhild Hoogeveen, Abstract Co-Author: Nothing to Disclose

Hans Heinz Schild MD, Abstract Co-Author: Nothing to Disclose

To evaluate fast dynamic, high spatial resolution contrast-enhanced (CE) 4D MR-DSA of arterial-venous malformations and fistulae at 3.0T and compare it with conventional DSA.

In a prospective study, CE MR angiography with 3D acquisition, image subtraction and high temporal resolution (4D MR-DSA) of the brain (n=19) and the feet/hand (n=2) was performed on a clinical whole body 3.0T MR system (Achieva; Philips Medical Systems, the Netherlands). In addition to parallel imaging with reduction factors of 3 in phase encoding and 2 in slice encoding (SENSE 3 x 2 = 6), the CENTRA keyhole method was used that acquires a central sphere (diameter, 16%) in a random order followed by elliptical centric readout of the periphery of k-space (T1w 3D gradient-echo; TR/TE/FA, 2.9-4.4 msec/1.0-1.4 msec/25°; 20 ml of Gd-DTPA at 2 ml/sec.). 29 (brain) and 6 (feet/hand) dynamic acquisitions of 1 sec. (brain) and 7.7 sec. (feet/hand) each were sampled at a spatial resolution of 1.1 x 1.4 x 1.1 mm³ and 0.7 x 0.9 x 1.0 mm³, respectively. MR images were reviewed on a work station and compared to DSA by two radiologists in consensus in order to depict feeding arteries and superficial/ deep venous drainage.

Dynamic information of the course of the contrast agent was seen in 21/21 (100%) and AVM or fistulae were diagnosed in 17/21. A speedup factor of 6 (CENTRA keyhole) x 6 (SENSE) = 36 was reached by 4D MR-DSA. 4D MR-DSA images allowed for correct identification of major feeding arteries (17/17) and deep (17/17) and superficial (17/17) venous drainage as compared to conventional DSA. Small arterial feeders (4/17) were better depicted on conventional DSA in comparison with 4D MR-DSA.

Fast dynamic, high spatial resolution 4D MR-DSA at 3.0T is a promising non-invasive technique to compete conventional DSA in the assessment of arterial-venous malformations and fistulae of the brain, hand and feet.

Willinek, W, Von Falkenhausen, M, Urbach, H, Gieseke, J, Hoogeveen, R, Schild, H, Fast Dynamic, High Spatial Resolution Contrast-enhanced 4D MR-DSA of Arterial-Venous Malformations and Fistulae at 3.0T.  Radiological Society of North America 2005 Scientific Assembly and Annual Meeting, November 27 - December 2, 2005 ,Chicago IL. http://archive.rsna.org/2005/4407343.html