Ulrich Linsenmaier MD, Presenter: Nothing to Disclose

Michael Krotz, Abstract Co-Author: Nothing to Disclose

T Vogel, Abstract Co-Author: Nothing to Disclose

P Biberthaler, Abstract Co-Author: Nothing to Disclose

KJ Pfeifer, Abstract Co-Author: Nothing to Disclose

M Reiser MD, Abstract Co-Author: Nothing to Disclose

Markus Korner MD, Abstract Co-Author: Nothing to Disclose

Johannes Rieger MD, Abstract Co-Author: Nothing to Disclose

et al, Abstract Co-Author: Nothing to Disclose

To evaluate whether MRI can detect additional intracerebral lesions in patients with negative CCT findings and elevated neuroprotein S-100B after minor head trauma (MHT).

In a prospective study 1150 consecutive patients with MHT were evaluated by standard CCT and determination of neuroprotein S-100B, a marker for traumatic brain injury (TBI). A cut off value for S100-B was determined before by linear regression and ROC-analysis. Patients with critically elevated S100-B and negative CCT received an additional MRI examination (T2w, T1w, T2*w and diffusion weighted sequences). All CCT and MRI images were evaluated by two independent radiologists for brain injury.

31/1150 (0.21%) patients with negative CCT studies and elevated S100-B (range 0.038-1.530, mean 0.475 ng/ml) underwent MRI. These MRI studies demonstrated intracerebral injuries in 7/31 (22.6%) cases: intracerebral hemorrhage (n=2) and subdural (n=1), epidural (n=0) and subarachnoid (n=4) hematomas. In 8/31 (25.8%) MRI revealed chronic cerebral ischemia, 6/31 (19.4%) had older parenchyma defects. In one case an acute cerebral infraction was detected.

MRI can detect additional acute injuries in patients with negative CCT and elevated S-100B however also chronic and ischemic lesions were detected.

Linsenmaier, U, Krotz, M, Vogel, T, Biberthaler, P, Pfeifer, K, Reiser, M, Korner, M, Rieger, J, et al, , Magnetic Resonance Imaging (MRI) Can Detect Intracerebral Injuries in Patients with Negative Cerebral Computed Tomography (CCT) after Minor Head Trauma (MHT) and Elevated Neuroprotein S-100B.  Radiological Society of North America 2004 Scientific Assembly and Annual Meeting, November 28 - December 3, 2004 ,Chicago IL. http://archive.rsna.org/2004/4416517.html