Wha-Young Kim MD, Presenter: Nothing to Disclose

In-One Kim, Abstract Co-Author: Nothing to Disclose

Woo Sun Kim MD, Abstract Co-Author: Nothing to Disclose

Hee Sun Park MD, Abstract Co-Author: Nothing to Disclose

1. To demonstrate ultrasonographic findings of bowels in experimentally induced necrotizing enterocolitis (NEC)with pathologic finding. 2. To demonstate the sensitivity of High Resolution Ultrasonography for detection of pneumatosis intestinalis in NEC.

We clamped superior mesenteric artery (SMA) of 20 rabbits. We performed bowel sonography (HDI 5000, Philips) before and after the procedure with one hour interval for 15-25 hours. We performed CT (Somatom Plus 4, Siemens) simultaneously with sonography in 10 rabbits. We could detect three patterns; echogenic spots in bowel wall (ES), circumferential granular echogenicities in bowel walls (CG) and hypoechoic thickened wall (HT). On pathology, ES (n=13) demonstrated villi and mucosal necrosis (13/13), congestion (13/13) and submucosal pneumatosis (3/13). CG (n=20) demonstrated severe mucosal necrosis (20/20), extensive submucosal pneumatosis (18/20) and inflammatory cells infiltration in muscle(3/20). HT (n=8) demonstrated submucosal edema (8/8) and tranmural infarction (4/8). On CT, bowel walls slightly thickened without evidence of pneumatosis. In conclusion, ES and CG corresponded to early stage of necrosis of bowels. HRUS can be useful modality for clinical diagnosis of NEC.

Kim, W, Kim, I, Kim, W, Park , H, Bowel Sonography in Necrotzing Enterocolitis with Histopathologic Correlation in Experimental Studies.  Radiological Society of North America 2004 Scientific Assembly and Annual Meeting, November 28 - December 3, 2004 ,Chicago IL. http://archive.rsna.org/2004/4416060.html