Andrew Frederick Scarsbrook BMBS, Presenter: Nothing to Disclose

Rajesh J Thakker, Abstract Co-Author: Nothing to Disclose

John A H Wass, Abstract Co-Author: Nothing to Disclose

Fergus V. Gleeson MBBS, Abstract Co-Author: Nothing to Disclose

Rachel Rhodes Phillips MD, Abstract Co-Author: Nothing to Disclose

To describe the varied clinicopathological features of multiple endocrine neoplasia and help increase understanding of disease behaviour.To illustrate the diverse imaging manifestations with special attention to characteristic diagnostic features.To discuss the role of different imaging modalities in initial diagnosis and disease monitoring.

Multiple endocrine neoplasia (MEN) is a group of rare disorders caused by genetic defects leading to hyperplasia, hyperfunction and malignancy involving two or more components of the endocrine system.There are two major forms of MEN referred to as type 1 and type 2. Each is characterized by the development of tumors within specific endocrine organs.Imaging plays a vital role in the diagnosis and management of the disease. We present a review of the diverse radiological features on cross-sectional and radionuclide imaging with specific reference to characteristic findings which may suggest the diagnosis. The contribution of each imaging modality is reviewed and suitable radiologic protocols are suggested.The genetic basis of the disease, its clinico-pathologic features and contemporary management is also discussed.

Scarsbrook, A, Thakker, R, Wass, J, Gleeson, F, Phillips, R, Multiple Endocrine Neoplasia: Spectrum of Radiological Appearances and Discussion of a Multi-technique Imaging Approach.  Radiological Society of North America 2004 Scientific Assembly and Annual Meeting, November 28 - December 3, 2004 ,Chicago IL. http://archive.rsna.org/2004/4405042.html