Abstract:
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Purpose: To investigate the feasibility of 3D-Rotational Coronary
Angiography (3D-RCA) for high-spatially resolved three-dimensional
reconstruction and visualization of the coronary arteries in the pig model.
Methods and Materials: Two-dimensional projections of the coronary artery tree
were acquired at a frame rate of 25fr/s during a rotation of the system gantry
over an angular span of 180deg at angular velocities of 30deg/s. During the
data acquisition contrast material (300mg/ml) was injected through a catheter
placed in the ostium of either the left or the right coronary artery tree. To
ensure constant filling of the artery tree over the entire rotational run, the
injection of contrast was initiated 1 to 2 sec before starting the gantry
rotation. 3D-RCA was performed in 8 pigs during suspended ventilation. The
heart reate of the animals ranged from 75 to 97bpm. The 8th animal had LCA
stenosis induced by balloon inflation 4 weeks prior to the angiography. After
data acquisition, a gated volume reconstruction using a slightly modified
Feldkamp technique was performed. Forward projections of the reconstructed
volumes were obtained and compared to the original projection data for
assessment of the accuracy of the reconstructions.
Results: In all cases volume reconstructions yielded an isotropic spatial
resolution of 200um using a gating window of 20ms length. Volumes reconstructed
from data obtained during end-diastole provide a clear visualization of the
coronary artery tree including proximal, medial and distal parts. By moving the
gating window over the cardiac cycle several temporal snapshots of the coronary
arteries could be provided, yielding a temporally resolved impression of the
coronary artery tree. The comparison of the forward projected volumes to the
original data sets showed excellent agreement indicating an accurate
reconstruction of the three-dimensional coronary artery structure for the
healthy arteries as well as for the stenotic artery.
Conclusion: The feasibility of 3D-RCA could be shown in the animal model. The
excellent results imply that data acquired over a single rotational run can
provide high quality morphological three-dimensional information of the
coronary arteries in the catheter laboratory allowing for objective quantification
of coronary artery lesions. (V.R., M.G., R.K. are employees of Philips
Research. R.S. is an employee of Philips Medical Systems.)
Questions about this event email: Volker.Rasche@philips.com
Rasche PhD, V,
ECG-gated 3D Rotational Coronary Angiography. Radiological Society of North America 2003 Scientific Assembly and Annual Meeting, November 30 - December 5, 2003 ,Chicago IL.
http://archive.rsna.org/2003/3106942.html
