RSNA 2019

Abstract Archives of the RSNA, 2019


NR343-ED-TUA10

WHO 2016 Classification of CNS Tumors: The Beginning of the Molecular Era

Tuesday, Dec. 3 12:15PM - 12:45PM Room: NR Community, Learning Center Station #10



Participants
Maria Emilia Paday Formenti, MD, Buenos Aires, Argentina (Presenter) Nothing to Disclose
Maximiliano Darakdjian, MD, Buenos Aires City, Argentina (Abstract Co-Author) Nothing to Disclose
Nadia I. Stefanoff, MD, Buenos Aires, Argentina (Abstract Co-Author) Nothing to Disclose
Maria M. Serra, MD, Buenos Aires, Argentina (Abstract Co-Author) Medical Advisor, EntelaiPic
Hernan Chaves, MD, Vicente Lopez, Argentina (Abstract Co-Author) Consultant, ENTELAI
Francisco Garagorry, MD, Buenos Aires, Argentina (Abstract Co-Author) Nothing to Disclose
Naomi Arakaki, MD, Buenos Aires, Argentina (Abstract Co-Author) Nothing to Disclose
Blanca Diez, Capital Federal, Argentina (Abstract Co-Author) Nothing to Disclose
Paulina Yanez, MD, Buenos Aires, Argentina (Abstract Co-Author) Nothing to Disclose

For information about this presentation, contact:

mepaday@fleni.org.ar

TEACHING POINTS

Review the updates of WHO classification of CNS tumors, highlighting the differences with previous classifications. Describe key imaging characteristics of the different entities on this group. Illustrate with cases from our institution, enhancing radio-pathologic and molecular correlation.

TABLE OF CONTENTS/OUTLINE

Major changes WHO 2016 classification: -Nomenclature -New and removed entities Astrocytic and oligodendroglial tumors: -Diffuse gliomas classification scheme based on IDH mutations and 1p/19q status -Glioblastoma: IDH mutant and IDH wild type -Epitheloid glioblastoma -Diffuse midline glioma, H3 K27M-mutant -Anaplastic xantoastrocitoma Embryonal tumors: -Medulloblastomas: WNT, SHH, group 3 and group 4 -Embryonal tumor with multilayered rosettes, C19MC-altered Neuronal and mixed glioneuronal lesions: -Diffuse leptomeningeal glioneuronal tumor (DLGT) -Multinodular vacuolar neuronal tumor (MVNT) Ependymal tumors: -Ependymoma, RELA fusion-positive Solitary fibrous tumor and hemangiopericitoma Atypical meningiomas with brain invasion Conclusion

Printed on: 03/01/22