The purpose of this exhibit is1) To familiarize radiologists with clinical indices of Crohn’s disease used by gastroenterologists, such as the Harvey Bradshaw Index, Crohn’s Disease Activity Index, Crohn’s Disease Endoscopic Index of Severity, and Simple Endoscopic Score for Crohn’s Disease.2) To describe, compare, and contrast indices for Crohn’s disease activity that use MR enterography findings, such as the Magnetic Resonance Index of Activity (MaRIA), Sailer index for anastomotic recurrence, Crohn's Disease MRI Index (CDMRI), and Clermont score. 3) To discuss concept of cumulative damage as assessed with Lemann index.
TABLE OF CONTENTS/OUTLINE1)Background and significance of Crohn’s disease2)Describe the need for reproducible indices of Crohn’s disease activity: Reliably distinguish active from inactive disease, Guide therapy decisions, & Importance in research3)Review clinical indices of Crohn’s disease: Symptom based vs Endoscopy based4)Review imaging based indices of Crohn’s disease using MR enterography: Describe indices & Provide examples of the relevant features and measurements5)Future directions and summary