RSNA 2016

Abstract Archives of the RSNA, 2016


MS142-ED-THB1

BRCA and Beyond: Comprehensive Image-Rich Review of Hereditary Breast and Gynecologic Cancer Syndromes

Thursday, Dec. 1 12:45PM - 1:15PM Room: MS Community, Learning Center Station #1



Awards
Identified for RadioGraphics

Stephanie N. Histed, MD, Los Angeles, CA (Presenter) Nothing to Disclose
Nina Woldenberg, MD, Los Angeles, CA (Abstract Co-Author) Nothing to Disclose
Rinat Masamed, MD, Los Angeles, CA (Abstract Co-Author) Nothing to Disclose
Melissa M. Joines, MD, Los Angeles, CA (Abstract Co-Author) Nothing to Disclose
Antoinette R. Roth, MD, Sylmar, CA (Abstract Co-Author) Nothing to Disclose
Maitraya K. Patel, MD, Sylmar, CA (Abstract Co-Author) Nothing to Disclose
TEACHING POINTS

Radiologists play a central role in guiding high-risk patients with hereditary breast and gynecologic cancers including patient identification, screening, diagnosis and staging. Familiarity with the associated genetic mutations, pathophysiology, incidence, specific cancer risks and image-based screening guidelines is needed for collaborative high level care of this high-risk patient population. Several hereditary cancer syndromes are associated with increased risk of breast, ovarian, endometrial and cervical cancer as well as other non-breast and gynecologic cancers. Multimodal image based screening may be indicated for these patients. Analyzing the presentation of these high-risk patients appropriately will guide diagnosis and management.

TABLE OF CONTENTS/OUTLINE

Image-rich comprehensive review of hereditary breast and gynecologic cancer syndromes, including hereditary breast and ovarian cancer associated with BRCA1/BRCA2 and Lynch syndrome, and less common syndromes including Peutz-Jegher, Gorlin, Li-Fraumeni and Cowden. Associated genetic mutations, pathophysiology, incidence, specific cancer risks and image-based screening guidelines. Discussion of the subtypes of breast, ovarian, endometrial and cervical cancer as well as non-breast and gynecologic cancers in each syndrome.