The purpose of this exhibit is to
1. Review molecular in vivo methods2. Review Specific Tumor Component marker of spectroscopy: physics of signal development, biochemical explanations, application in breast imaging3. Review spectral methods in monitoring neoadjuvant chemotherapy: generation of scatter-corrected absorption spectrum, the wavelength dependent changes during chemotherapy, implications for prognosis
The purpose of this exhibit is to1. Review molecular in vivo methods: focus on absorption spectroscopy, fundamentals of light, derivation of tissue characterization, patterns of functional changes in normal/disease states2. Review the Specific Tumor Component-Explain mathematics for quantification of the Specific Tumor Component marker-Demonstrate selection of the wavelength regions-Review the index signal for normal/cancerous tissues-Describe clinical implications of quantification of functional changes3. Review spectral methods in monitoring neoadjuvant chemotherapy: -Show scatter corrected absorption spectrum-Demonstrate main points of wavelength specific spectral variation-Explain clinical correlation of tissue absorber during neoadjuvant chemotherapy-Describe clinical utility for prognosis4. Summary5. Future directions of molecular imaging in breast cancer