RSNA 2010 

Abstract Archives of the RSNA, 2010


SSQ01-08

Prior Mammography in Women Aged 40-50 at a UK Center in Accordance with ACS Guidelines Lowers Mastectomy Rate Following Breast Cancer

Scientific Formal (Paper) Presentations

Presented on December 2, 2010
Presented as part of SSQ01: ISP: Breast Imaging (Tomosynthesis and Digital Mammography)

Participants

Nicholas Mark Perry MD, Presenter: Nothing to Disclose
Sue Elizabeth Milner BSC, Abstract Co-Author: Nothing to Disclose
Kefah Mokbel MD, Abstract Co-Author: Nothing to Disclose
Stephen W. Duffy, Abstract Co-Author: Nothing to Disclose
Katja Pinker MD, Abstract Co-Author: Nothing to Disclose

PURPOSE

To compare the mastectomy rate following breast cancer at a UK center in women aged 40-50 with a prior mammogram at one year, to those with longer interval, or no previous mammography.

METHOD AND MATERIALS

There are no national guidelines recommending routine breast screening for women aged 40-50 in the UK. At a London specialist breast center, 971 women had breast cancer diagnosed between 2003 and 2009. At time of diagnosis, 393 (40%) were aged under 50. Of these, 156 women aged 40-50 were treated at our center and had full clinical data available. Information on prior mammography and primary surgical treatment was retrieved from patient records. We compared the number of women receiving mastectomy (as opposed to breast conserving surgery) by history of prior mammography and age, using the chi-squared test.

RESULTS

Of the 156 women, 114 (73%) had no previous mammograms. 42 (27%) had prior mammography, 29 (19%) within two years. 16(10%) women had mammography one year previously. Mastectomy was the required treatment for 3 (19%) of the 16 women with a prior mammogram at one year, compared with 64 (46%) of the140 women who had not had a mammogram in the past year. This difference was significant (p=0.04).

CONCLUSION

In women aged 40-50 with breast cancer diagnosed at our UK center, only 10% had undergone prior mammography in accordance with American Cancer Society guidelines. These women had a mastectomy rate of less than half the others (19% vs. 46%).

CLINICAL RELEVANCE/APPLICATION

Regular screening allows greater likelihood of conservative surgery for breast cancer. Our results support the benefit of breast screening for women aged 40-50 years on an annual basis.

Cite This Abstract

Perry, N, Milner, S, Mokbel, K, Duffy, S, Pinker, K, Prior Mammography in Women Aged 40-50 at a UK Center in Accordance with ACS Guidelines Lowers Mastectomy Rate Following Breast Cancer.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9012348.html