Themistoklis Nikolaos Spyridopoulos MD, Presenter: Nothing to Disclose

Chrisovalandis J. Vergadis MD, Abstract Co-Author: Nothing to Disclose

Alexia Balanika DSc, Abstract Co-Author: Nothing to Disclose

Stylianos Argentos MD, Abstract Co-Author: Nothing to Disclose

Efthymia Alexopoulou, Abstract Co-Author: Nothing to Disclose

Elias Brountzos, Abstract Co-Author: Nothing to Disclose

To evaluate the prevalence of incidental severe renal arterial stenosis (RAS) and its potential risk factors in patients with peripheral arterial disease (PAD).

Over a two-year period (January 1, 2006 through December 31, 2007), 368 consecutive patients undergoing angiographic evaluation of symptomatic lower extremity PAD were studied. Statistical analysis was performed to determine the association of RAS (>60% diameter stenosis) with demographic /somatometric parameters (age, sex, gender, BMI, smoking ), medical history variables (hypertension, diabetes mellitus,hyperlipidemia, coronary artery disease, renal dysfunction laboratory values (blood creatinine, fasting glucose, total cholesterol, LDL, HDL and triglicerides) and distribution of PAD (aortoiliac, femoropopliteal, crural and multisegment disease). Data was analysed using a statistical software package, SPSS 11.5.

Study population included 80% males. One out of six patients had an incidental finding of stenosis > 60% in either renal artery. Statistically significant risk factors associated with the presence of RAS included age (p=0.01), hypertension (p=0.01), renal insufficiency (p<0.01) and and multisegment atherosclerotic disease (p=0.04). The incidence of renovascular hypertension was estimated about 4%.

Advance age, hypertension, renal insufficiency and and multisegment atherosclerotic disease are prognostic factors for severe renal artery stenosis among patients with peripheral arterial disease. The incidence of renovascular hypertension in this study group is relatively low, close to that reported in the general hypertensive population.

Severe renal artery stenosis is common among aged patients with hypertension, renal insufficiency and multisegment atherosclerotic lesions.

Spyridopoulos, T, Vergadis, C, Balanika, A, Argentos, S, Alexopoulou, E, Brountzos, E, Clinical Prognostic Factors for Severe Renal Artery Stenosis among Atherosclerotic Patients.  Radiological Society of North America 2008 Scientific Assembly and Annual Meeting, February 18 - February 20, 2008 ,Chicago IL. http://archive.rsna.org/2008/6010281.html