Abstract:
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Purpose: To describe differential imaging features of renal tumors on contrast-enhanced harmonic imaging, Agent Detection Imaging(ADI) as compared with those of CT scan.
Methods and Materials: Consecutive 40 patients with 40 renal solid tumors confirmed by surgery and biopsy were included in this study: 20 renal cell carcinomas (RCCs), 10 transitional cell carcinomas (TCCs), and 10 angiomyolipomas (AMLs). All 40 patients were examined with ADI in conjunction with a galactose-based microbubble contrast agent (SH U 508A) and with interval delay scanning and triphasic helical CT scan including unenhanced, corticomedullary phase, and excretory phases. The pattern and the time of contrast enhancement were recorded on ADI images and plotted with time-signal intensity curves.
Results: Almost RCCs (90%, n=18) showed strong contrast signal in entire tumors except cystic and necrotic area with early wash-in and early wash-out pattern, whereas signals of all TCCs were absent or minimal, seen as a signal defect through all phases with contrast to normal renal parenchyma (P<0.05). All AMLs revealed persistent contrast signals in central (n=3) or peripheral (n=7) area of tumors from early to delayed phase (up to 5 min) (P<0.05). Three cases of RCC and 4 cases of AML with minimal fat component that were difficult to be differentiated respectively from TCCs and RCCs on CT scan were preoperatively able to make a correct diagnosis of with ADI scans.
Conclusion: Contrast-enhanced harmonic imaging with ADI scan is expected to be a promising diagnostic tool to upgrade current US role and thus to be a good alternative imaging technique to CT scan.
Questions about this event email: rapark@radiol.snu.ac.kr
Park MD, B,
Renal Tumors: Differentiations with Contrast-enhanced Harmonic Imaging (Agent Detection Imaging). Radiological Society of North America 2003 Scientific Assembly and Annual Meeting, November 30 - December 5, 2003 ,Chicago IL.
http://archive.rsna.org/2003/3106711.html
