RSNA 2003 

Abstract Archives of the RSNA, 2003


K14-982

Role of T2*-weighted first pass perfusion MR imaging in head & neck tumors

Scientific Papers

Presented on December 3, 2003
Presented as part of K14: Neuroradiology/Head and Neck (Head and Neck Cancer: Staging and Recurrence)

Participants

Ahmed Abdel Razek MD, PhD, PRESENTER: Nothing to Disclose

Abstract: HTML Purpose: To determine the role of T2*- weighted first pass perfusion MR imaging in head and neck tumors. Methods and Materials: Thirty-eight head and neck masses in 31 patients underwent multislice single shot EPI T2*-weighted first pass perfusion MR imaging using 1.5 tesla unit. Bolus infusion of Gadolinium-DTPA was administrated in a dose of 0.2ml mol/ kg BW after 8 seconds of baseline acquisition. Image acquisition was repeated every 2 seconds and data acquisition time was 120 seconds. Imaging parameters were: TR=120ms, TE=47ms, slice thickness=5mm, gap=2mm.& NEX=1. The images were processed and lesion signal intensity versus time curve was created for quantitative analysis. The parameters investigated were: maximum signal intensity (SI) loss, time to reach maximum SI loss and SI recovery time. These parameters were compared with histopathological findings and clinical outcome. Results: In malignant head and neck tumors (n=25), the mean maximum SI loss was 57.3±15%, the time to reach maximum SI loss was 6.2±2.1sec & SI recovery after 14.7±3.1sec. The mean maximum SI loss of benign lesions (n=13) was 32.74±7%, the time to reach maximum SI loss was 8.6±2.2sec & SI recovery after 8.2±1.3sec. There was statistically difference for maximum SI loss (p<0.01) & time for SI recovery (p<0.03) and insignificant difference for time for maximum SI loss (p=0.1) between benign and malignant head and neck tumors. Conclusion: T2*-weighted first pass perfusion MR imaging has a significant role in differentiation benign from malignant head and neck tumors with a higher degree of certainty. The high specificity of T2*-weighted first perfusion imaging probably reflects difference in vascularization, with higher vessel number and larger vessel diameter in malignant tumors. These preliminary results encourage the continued development of MR techniques for mapping of tumor vascularity in head and neck tumors.       Questions about this event email: arazek@mans.eun.eg

Cite This Abstract

Abdel Razek MD, PhD, A, Role of T2*-weighted first pass perfusion MR imaging in head & neck tumors.  Radiological Society of North America 2003 Scientific Assembly and Annual Meeting, November 30 - December 5, 2003 ,Chicago IL. http://archive.rsna.org/2003/3100325.html